The species-specific organizational property of speech is a continual mouth open-close alternation, the two phases of which are subject to continual articulatory modulation. The cycle constitutes the syllable, and the open and closed phases are segments framescontent displays that are prominent in many nonhuman primates. The new role of Broca's area and its surround in human vocal communication may have derived from its evolutionary history as the main cortical center for the control of ingestive processes. The frame and content components (...) of speech may have subsequently evolved separate realizations within two general purpose primate motor control systems: (1) a motivation-related medial system, including anterior cingulate cortex and the supplementary motor area, for self-generated behavior, formerly responsible for ancestral vocalization control and now also responsible for frames, and (2) a lateral system, including Broca's area and surround, and Wernicke's area, specialized for response to external input (and therefore the emergent vocal learning capacity) and more responsible for content. (shrink)

An action-oriented perspective changes the role of an individual from a passive observer to an actively engaged agent interacting in a closed loop with the world as well as with others. Cognition exists to serve action within a landscape that contains both. This chapter surveys this landscape and addresses the status of the pragmatic turn. Its potential influence on science and the study of cognition are considered (including perception, social cognition, social interaction, sensorimotor entrainment, and language acquisition) and its impact (...) on how neuroscience is studied is also investigated (with the notion that brains do not passively build models, but instead support the guidance of action). A review of its implications in robotics and engineering includes a discussion of the application of enactive control principles to couple action and perception in robotics as well as the conceptualization of system design in a more holistic, less modular manner. Practical applications that can impact the human condition are reviewed (e.g., educational applications, treatment possibilities for developmental and psychopathological disorders, the development of neural prostheses). All of this foreshadows the potential societal implications of the pragmatic turn. The chapter concludes that an action-oriented approach emphasizes a continuum of interaction between technical aspects of cognitive systems and robotics, biology, psychology, the social sciences, and the humanities, where the individual is part of a grounded cultural system. (shrink)

Essays that put noted political thinkers of the past—including Plato, Machiavelli, Hobbes, Wollstonecraft, Marx, and Confucius—in dialogue with current environmental political theory. Contemporary environmental political theory considers the implications of the environmental crisis for such political concepts as rights, citizenship, justice, democracy, the state, race, class, and gender. As the field has matured, scholars have begun to explore connections between Green Theory and such canonical political thinkers as Plato, Machiavelli, Locke, and Marx. The essays in this volume put important figures (...) from the political theory canon in dialogue with current environmental political theory. It is the first comprehensive volume to bring the insights of Green Theory to bear in reinterpreting these canonical theorists. Individual essays cover such classical figures in Western thought as Aristotle, Hume, Rousseau, Mill, and Burke, but they also depart from the traditional canon to consider Mary Wollstonecraft, W. E. B. Du Bois, Hannah Arendt, and Confucius. Engaging and accessible, the essays also offer original and innovative interpretations that often challenge standard readings of these thinkers. In examining and explicating how these great thinkers of the past viewed the natural world and our relationship with nature, the essays also illuminate our current environmental predicament. Essays on Plato • Aristotle • Niccolò Machiavelli • Thomas Hobbes • John Locke • David Hume • Jean-Jacques Rousseau • Edmund Burke • Mary Wollstonecraft • John Stuart Mill • Karl Marx • W. E. B. Du Bois • Martin Heidegger • Hannah Arendt • Confucius Contributors Sheryl D. Breen, W. Scott Cameron, Peter F. Cannavò, Joel Jay Kassiola, Joseph H. Lane Jr. Timothy W. Luke, John M. Meyer, Özgüç Orhan, Barbara K. Seeber, Francisco Seijo, Kimberly K. Smith, Piers H. G. Stephens, Zev Trachtenberg, Andrew Valls, Harlan Wilson. (shrink)

Literary difficulties vary. Certain genres are "easier" than others. And a knowledge of the historical process, involving what is called convention certainly seems to make difficult works easier. Such is the case of courtly lyrics. They are "simple" and essentially conventional; a reader knows what to expect in them. But the problem of literary difficulties remains there too. The essential difficulties of courtly lyrics are under the surface. They become apparent to a more careful, more thoughtful reader. The realization that (...) such difficulties exist is the first step toward studying them, and only through studying them can we appreciate the real aesthetic wealth of courtly poetry and, I believe, of most of the poetry of other ages and other cultures. Peter F. Dembowski is the author of La Chronique de Robert Clari: Etude de la langue et du style and the editor of critical editions of Old French chansons de geste. His recent edition of all known Old and Middle French versions of the Life of Saint Mary of Egypt appears in the series, Publications françaises et romanes. (shrink)

A revision of the author's thesis, Harvard University, 1967.

Among the objections to the implementation of what I will call "genome editing in human reproduction" is that it does not address any unmet medical need, and therefore fails to meet an important criterion for introducing an unproven procedure with potentially adverse consequences. To be clear: what I mean by GEHR is the use of any one of a number of related biological techniques, such as the CRISPR-Cas9 system, deliberately to modify a functional sequence of DNA in a cell of (...) a human embryo, so that the modified sequence is replicated in the cells of a resulting child and may, without further intervention, be passed on to that child's biological descendants. It is... (shrink)

This paper examines how people in West Africa are reacting to the Ebola virus disease, an epidemic presently prevalent in the region. Certain lifestyle changes are suggested. Additionally, the heart of the paper focuses on the request by governments to be allowed access to experimental drugs, such as Zmapp and TKM-Ebola, for their infected populations. The author argues that granting such a request would circumvent research ethics procedures, which could potentially constitute significant risk to users of the drugs. The Pfizer (...) Kano meningitis trial of 1996 is cited as an example to buttress how unapproved drugs could prove fatal. (shrink)

The Frame/Content theory deals with how and why the first language evolved the present-day speech mode of programming syllable “Frame” structures with segmental “Content” elements. The first words are considered, for biomechanical reasons, to have had the simple syllable frame structures of pre-speech babbling, and were perhaps parental terms, generated within the parent–infant dyad. Although all gestural origins theories have iconicity as a plausible alternative hypothesis for the origin of the meaning-signal link for words, they all share the problems of (...) how and why a fully fledged sign language, necessarily involving a structured phonology, changed to a spoken language. (shrink)

Henry David Thoreau, though often characterised as individualist or apolitical, is in fact an important link between Jeffersonian agrarian republicanism and environmentalism. Like the Jeffersonians, Thoreau espouses a political economy of citizenship, criticises modern capitalism, and celebrates simplicity and personal independence. However, Thoreau rejects the Jeffersonians' focus on conquest of the wilderness and economic industriousness, both of which were meant to promote virtue. Thoreau advocates preservation of wild nature as essential for cultivating virtue and regards nature as a community deserving (...) respect and protection. He criticises an emphasis on economic industriousness as promoting overwork, environmental destruction and greed. Thoreau emerges as a complex figure whose legacy points in two contrasting directions: toward a more ecologically responsible or sustainable republicanism embracing preservation of a spectrum of landscapes from wilderness to agrarian, and also toward a problematic, depoliticising separation between human beings and nature. (shrink)

Human ritual sacrifices are one of the cultural practices that are undertaken in Nigeria and in many West African countries. While such ritual sacrifices are utilized for different purposes, this paper, however, focuses on baby farming for the purpose of human child ritual sacrifice for community and individual utilizations. Recruiting women for the sole purpose of using them for procreation is exploitative as such young women are usually in dire economic situations. Baby farmers identify the economic vulnerabilities of such women (...) and make them offers they cannot refuse. In like manner, helpless children who are harvested from the farms and who suffer gruesome deaths must be considered as the greatest victims in baby farming and harvesting arrangements. The paper stresses the need for stricter government vigilance and community sensitization to the horror of killing babies for sacrifice. (shrink)

This essay is an intercultural dialogue in reproductive ethics. The paper, which argues from both developed and developing world perspectives, addresses the question of what should be done when confronted with the possibility of giving birth to a severely disabled child. The author argues that such a life should not be considered because of the economic circumstances in most developing countries. This is contrary to the view sometimes advanced in affluent societies that the prevention of such a birth should not (...) necessarily be considered. The author, however, agrees that the principle of acceptable outlook could be employed in both economic settings but with a variable degree of moral compliance without suggesting that certain lives are better than others. (shrink)

The outbreak of the novel coronavirus pandemic, otherwise known as COVID-19 brought about the use of new terminologies—new lexical items such as social distancing, self-isolation, and lockdown. In developed countries, basic social amenities to support these are taken for granted; this is not the case in West African countries. Instead, those suggested safeguards against contracting COVID-19 have exposed the infrastructural deficit in West African countries. In addition, and more profoundly, these safeguards against the disease have distorted the traditional community-individuality balance. (...) The enforcement of social distancing, self-isolation, and lockdown has made it impossible for West Africans to drift to their ancestral homes and villages, as is usually the case in times of crisis, with attendant consequences for communal life and traditional burial rites. This could be one of the reasons why some COVID-19 patients are escaping from isolation centres, since to die in such centres violates their bodily integrity at an ontological level. (shrink)

Current diagnostic criteria for schizophrenia place emphasis on delusions and hallucinations, whereas the classical descriptions of schizophrenia by Kraepelin and Bleuler emphasized disorganization and impoverishment of mental activity. Despite the availability of antipsychotic medication for treating delusions and hallucinations, many patients continue to experience persisting disability. Improving treatment requires a better understanding of the processes leading to persisting disability. We recently introduced the term classical schizophrenia to describe cases with disorganized and impoverished mental activity, cognitive impairment and predisposition to persisting (...) disability. Recent evidence reveals that a polygenic score indicating risk for schizophrenia predicts severity of the features of classical schizophrenia: disorganization, and to a lesser extent, impoverishment of mental activity and cognitive impairment. Current understanding of brain function attributes a cardinal role to predictive coding: the process of generating models of the world that are successively updated in light of confirmation or contradiction by subsequent sensory information. It has been proposed that abnormalities of these predictive processes account for delusions and hallucinations. Here we examine the evidence provided by electrophysiology and fMRI indicating that imprecise predictive coding is the core pathological process in classical schizophrenia, accounting for disorganization, psychomotor poverty and cognitive impairment. Functional imaging reveals aberrant brain activity at network hubs engaged during encoding of predictions. We discuss the possibility that frequent prediction errors might promote excess release of the neurotransmitter, dopamine, thereby accounting for the occurrence of episodes of florid psychotic symptoms including delusions and hallucinations in classical schizophrenia. While the predictive coding hypotheses partially accounts for the time-course of classical schizophrenia, the overall body of evidence indicates that environmental factors also contribute. We discuss the evidence that chronic inflammation is a mechanism that might link diverse genetic and environmental etiological factors, and contribute to the proposed imprecision of predictive coding. (shrink)

We endorse Davey's view that expectancy processes are intimately involved in fear reactions, but question his model on three grounds. First, the mechanism for generating expectancy bias to both ontogenetic and phylogenetic stimuli is not spelled out. Second, the selective association component is unnecessary. Third, the model fails to provide a clear explanation for the irrationality of phobic reactions.

Dans cet article, l'A. nous propose une solution à un vexant problème théologique, à savoir la façon dont la vision béatifique complète la nature humaine tout en demeurant un don au delà du don divin qui est notre être naturel. En se penchant sur l'oeuvre de Thomas d'Aquin, Ryan encadre d'abord le problème. Ensuite il étudie l'émergence de la théorie dite de «pure nature» comme réponse à Baius, lequel affirmait qu'avant la chute d'Adam la vision béatifique n'était que le complément, (...) dû nécessairement à la nature humaine. L'auteur nous présente également la défense offerte par Garrigou-Lagrange de la théorie de «pure nature», ainsi que la critique offerte par de Lubac. Nous remarquons effectivement que la prise de position des partisans de «pure nature» et celle adoptée par de Lubac se réfutent mutuellement. Ensuite nous étudions la position de Rahner. Selon Ryan, l'apport de Rahner est important; cependant une solution basée sur «l'existentiel surnaturel» rahnerien reste intenable. En fin de compte, l'auteur nous propose une solution qui tire profit de ces points de vue divergents, tout en évitant les pièges qui les accompagnent. (shrink)

Thomas d'Aquin pense que tout homme dirige nécessairement toutes ses actions vers une fin ultime unique. L'article rejette cette position et son présupposé que tout homme cherche nécessairement une béatitude parfaite qui ne laisse rien à désirer. L'article affirme au contraire que les hommes agissent souvent de façon simultanée en vue de plus d'une fin dernière. Ceux qui pèchent mortellement le font en commettant des actions gravement mauvaises, tout en croyant et espérant en Dieu. Ceux qui vivent dans la grace (...) sont supposés avoir Dieu pour leur fin derniere unique. Cependant, tout péché véniel délibéré est commis pour une autre fin ultime. En fait, les gens posent souvent des actions moralement bonnes pour une fin ultime autre que Dieu, car la foi vivante n'informe pas automatiquement toute la vie. On doit apprendre à chercher d'abord le Royaume de Dieu, conçu comme incluant non seulement le bien infini mais aussi les biens créés dans lesquels les coeurs inquiets des hommes trouvent leur accomplissement intégral. (shrink)